Stem Cell Research
Coaxing induced pluripotent stem cells down defined lineages — and reading the transcriptional decisions that make one daughter cell a neuron and its sibling something else entirely.
I study how a single cell decides to divide, differentiate, and die — mapping the molecular machinery that keeps living tissue in balance, and how cancer learns to break its rules.
Four overlapping questions about how cells build, maintain, and occasionally betray the tissues they belong to.
Coaxing induced pluripotent stem cells down defined lineages — and reading the transcriptional decisions that make one daughter cell a neuron and its sibling something else entirely.
Tracing signaling cascades and gene-regulatory circuits that translate an external cue into a cell-fate commitment.
Investigating how tumour cells silence the checkpoints that normally force a damaged cell to stop dividing — and where those escape routes stay vulnerable.
Capturing organelles in motion — mitochondrial fission, spindle assembly, membrane trafficking — with multi-channel fluorescence and quantitative image analysis.
3D culture that lets tissue self-organise in a dish.
Read it like a chromosome — each base a place where the work turned toward something new.
First contact with the fluorescence microscope — and the realisation that a cell is not a bag of chemicals but a decision-making system.
Built live-imaging pipelines to track lineage commitment in real time, quantifying how signalling noise shapes cell-fate choice.
Dissected checkpoint-escape mechanisms in patient-derived tumour models; co-authored work on apoptosis resistance.
Combining organoid models with high-content imaging to ask how tissues repair themselves — and why that programme fails.
Selected work in cell-fate regulation and quantitative live-cell imaging. Full list available on request.
See the latest on LinkedIn ↗Negin is a Biology Student at Islamic Azad University, working in cellular & molecular biology. Whether it's a research partnership, a question, or a conversation about where cell biology is heading — the channel is open.